University of Barcelona

Ahead of the anticipated conclusion of a United Nations global treaty on plastics, a group of international experts calls for greater attention to health effects when addressing plastic pollution. The work, published in The Lancet, reviews current evidence on how plastics—including microplastics and plastic chemicals—affect health, and announces the launch of a new project to monitor these effects.

Between 2021 and 2024, the Android Earthquake Alerts system detected an average of 312 earthquakes per month and sent alerts in 98 countries associated with 60 events of magnitude greater than 4.5, according to a study published in the journal Science. The study also includes comments from users who received the alerts: 85% said they felt tremors, 36% received the alert before noticing them, 28% during the event and 23% after they occurred. In addition, 84% said they would trust the system more next time, according to the research team from Google and the universities of California - Berkeley and Harvard (USA).

In Spain, immigrant employees earn 29% less than other workers, according to a study published in Nature. This gap is comparable to that observed in Canada, but greater than that of other European countries in the study, such as Germany, Norway and France (19-20%), and much higher than the gap observed in the United States (10%) and Sweden (7%). ‘The segregation of immigrant workers into lower-paid jobs accounts for approximately three-quarters of the overall wage differences between immigrants and natives,’ the study states.

A team from the Netherlands has successfully edited pathogenic mutations in mitochondrial DNA in human cells, changes in DNA that cause disease, according to research published in PLoS Biology. The authors used a genetic tool known as a base editor. Until now, techniques derived from CRISPR have made it possible to correct mutations in nuclear DNA, and new techniques are being developed that allow mitochondrial DNA to be edited.

An oral formulation of risperidone could be administered weekly instead of daily to treat patients with schizophrenia with the same efficacy, according to a phase III clinical trial published in The Lancet Psychiatry. The study included 83 patients in the United States.

An international study has warned of the potential risks of widespread use of faecal microbiota transplantation without taking into account the region of the intestine where the transferred microbes arrive. The experiment, conducted on mice and human tissue samples, showed that the microbes from the transplant—mostly anaerobic microbes from the colon—colonised the small intestine, persisted there for months and modified that new environment, causing changes in the host's metabolism. According to the authors, whose study is published in the journal Cell, this may have long-lasting and unforeseen consequences, as well as imbalances in the intestinal ecosystem of patients.

A technique developed under the coordination of researchers from the Centre for Genomic Regulation (CRG) and the Institute for Biomedical Research (IRB) in Barcelona has made it possible to track methylation patterns or “barcodes” in blood cells and construct their epigenetic family tree. This has enabled them to trace their evolution and changes with age, which could be useful for disease prevention and for the study or even development of specific therapies against ageing. The results are published in the journal Nature.

A team from the Children's Hospital of Philadelphia and Penn Medicine (United States) has successfully treated a baby diagnosed with a rare genetic disorder using personalised CRISPR gene editing therapy. The baby, known only by the initials KJ, was born with a rare metabolic disease known as severe carbamoyl phosphate synthetase 1 (CPS1) deficiency. After spending the first months of his life in hospital on a very restrictive diet, KJ received the first dose of his tailored therapy in February 2025, between six and seven months of age. The treatment, which is being used for the first time for this type of disorder, was administered safely, and the baby is now growing well and improving. The case is detailed in a study published by The New England Journal of Medicine (NEJM).

A research team has managed to ‘rejuvenate’ embryonic stem cells from mice to give them greater differentiation potential, according to an article published in the EMBO Journal. Changing the type of sugar these cells use to grow modifies their metabolism and, according to the researchers, could improve their therapeutic potential or their use in in vitro fertilisation treatments.  

A new study sheds light on how the brain adjusts its ‘wiring’ during learning, concluding that different dendritic segments of the same neuron follow different rules for communicating through their connections - synapses. The findings challenge the idea that neurons follow a single learning strategy and offer a new perspective on how the brain learns and adapts its behaviour. The work, carried out in mice, is published in the journal Science.