Complutense University of Madrid

A century ago, astronomer Fritz Zwicky observed that galaxies were moving faster than their mass should allow, leading him to infer the presence of an invisible structure, dark matter. Since the particles that make up dark matter do not interact with electromagnetic force, they cannot be observed directly, as they do not absorb, reflect, or emit light. Now, NASA's Fermi space telescope has found specific gamma rays in the center of the Milky Way that are consistent with the decay of theoretical dark matter particles, although they could also come from other sources. “If this is correct, to my knowledge, it would be the first time that humanity has ‘seen’ dark matter,” said study author Tomonori Totani in a press release. The article is published in the Journal of Cosmology and Astroparticle Physics.

A new article published in eClinicalMedicine measures mental health problems in the Gaza Strip among the population over 40 years of age before and after the genocide committed by Israel. The study indicates that the proportion of these adults experiencing high levels of distress has tripled in the last five years, with a peak following the escalation of the massacre since October 2023. It was already known that chronic stress factors affecting victims pose a serious threat to mental health, but no longitudinal study had yet been conducted comparing distress in the same individuals before and after the genocide.  

A review conducted by the Cochrane Collaboration analyzed the effects of colchicine—a medication commonly used to treat some rheumatic diseases—on people who had already experienced a cardiovascular event. The review included 12 clinical trials with more than 23,000 patients and concluded that colchicine reduces the risk of stroke or heart attack in these individuals. Overall, for every 1,000 people treated, there were 9 fewer heart attacks and 8 fewer strokes compared to those who did not take the medication, with no apparent serious side effects.

A study by the University of Cádiz has identified six factors that drive polarization around health-related issues, for example during crises such as the COVID-19 pandemic: political ideology, misinformation, social media dynamics, trust in institutions and professionals, risk perception, and socioeconomic factors. This review, published in Science Advances, brings together the conclusions of 90 previous studies and analyzes how these determinants exacerbate health inequalities and influence compliance with public health measures.

A meta-analysis concludes that the use of beta-blockers is not necessary in patients who have suffered a heart attack but have normal cardiac function. The research, coordinated in Spain by the CNIC, brings together data from five clinical trials and 17,801 patients. One of these trials, REBOOT, already showed that patients who did not have reduced cardiac function after a heart attack did not benefit from treatment with beta blockers. According to this recent meta-analysis, published in the New England Journal of Medicine and presented at the American Heart Association Congress in New Orleans (USA), the use of these drugs does not reduce mortality, reinfarction or heart failure in this group of patients.

Severe combined immunodeficiency due to ADA enzyme deficiency is a rare disease that, without treatment, usually causes death within the first two years of life. These "bubble children" are currently treated with a bone marrow transplant or with injections that aim to restore, to the extent possible, the function of this enzyme. Now, an international team presents the results of a gene therapy administered to 62 children with the disease between 2012 and 2019. The therapy was effective in 95% of cases and did not cause serious complications, according to the authors, whose work is published in the journal NEJM. 

The Karolinska Institute has awarded the Nobel Prize in Medicine or Physiology to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi for describing how the immune system is regulated so as not to harm us. His groundbreaking discoveries on peripheral immune tolerance have spurred the development of new treatments for cancer and autoimmune diseases.

The use of creatine among athletes is not new, although its consumption has become popular on social media. We answer questions about this compound with the help of experts in nutrition, sports and dietetics.

A US team has analyzed the evolution of the global population exposed to forest fires between 2002 and 2021. The study indicates that the number of people exposed has increased by 40%, despite a 26% reduction in the area burned. This is mainly due to the increase in the population living in urban-forest interfaces. 85% of exposures occurred in Africa, even though forest fire disasters in North America, Europe, and Oceania have received most of the attention, notes the study, which is published in the journal Science.  

Light pollution is causing birds to sing more, prolonging their vocalisations by an average of 50 minutes, according to a study published in Science. The study, which analyses more than 580 species of diurnal birds, shows that those most exposed to light, either because they have large eyes or open nests, are the most affected by this phenomenon. The authors analysed more than 60 million vocalisations from the BirdWeather citizen science project. ‘The machine learning algorithm allows us to analyse audio recordings 24 hours a day, seven days a week, which would otherwise take a lifetime to listen to,’ says Breant Pease, one of the authors.