Barcelona Supercomputing Center (BSC)

At the current rate of carbon dioxide emissions, the 1.5°C temperature increase limit set in the Paris Agreement will be exceeded in four years. This is one of the predictions of the Global Carbon Budget 2025, the global report on the carbon balance, now in its 20th edition, which will be presented at COP30 in Belém (Brazil). Pep Canadell, one of its authors, analyzed its findings at a briefing organized by SMC Spain.

An Italian team has studied the factors that are increasing the frequency of massive floods in the Mediterranean region. According to their analysis, and in a context of climate change, a “dead end” effect is occurring in which mountains close to the sea block moisture and “trap” rain over the region. The article focuses on the floods suffered by the Emilia-Romagna region (Italy), but according to the authors, other Mediterranean areas with a similar geography, including Valencia and Catalonia, “could face the same risks and these events could become more frequent as the climate continues to change.” The results are published in Scientific Reports.  

The Royal Swedish Academy of Sciences has awarded the 2025 Nobel Prize in Physics to John Clarke, Michel H. Devoret, and John M. Martinis, who demonstrated both the quantum tunnelling effect and quantised energy levels in a system small enough to fit in the palm of your hand. These advances have served to develop the next generation of quantum technology, including quantum cryptography, quantum computers and quantum sensors.

Artificial intelligence (AI)-assisted protein engineering is enabling advances in the design of new molecules, but it also poses biosafety challenges related to the potential production of harmful or dangerous proteins. Some of these threats, whether deliberate or accidental, may not be detected by current control tools. An international team has analyzed the situation and developed software patches to improve their identification, although they acknowledge that it remains incomplete. The authors of the study, published in the journal Science, warn that some of the data and code should not be published in a public repository due to its potential misuse.

An international study has warned of the potential risks of widespread use of faecal microbiota transplantation without taking into account the region of the intestine where the transferred microbes arrive. The experiment, conducted on mice and human tissue samples, showed that the microbes from the transplant—mostly anaerobic microbes from the colon—colonised the small intestine, persisted there for months and modified that new environment, causing changes in the host's metabolism. According to the authors, whose study is published in the journal Cell, this may have long-lasting and unforeseen consequences, as well as imbalances in the intestinal ecosystem of patients.

A team led by the Centre for Genomic Regulation (CRG) in Barcelona and the Institute for Bioengineering of Catalonia (IBEC) has developed and used a new artificial intelligence (AI) tool called CANYA, together with a large volume of data, to predict when and why protein aggregation takes place. The resource could be used to advance research into neurodegenerative diseases and drug production, according to the joint press release. The results are published in the journal Science Advances.

US President Donald Trump has announced that all goods imported into the United States will be subject to a 10 % tariff. In the case of goods from the European Union, this will increase to 20 %, according to the executive order signed by Trump, which will affect the EU's science and health industry. This tariff will be even higher with other trading partners. The measure will not affect pharmaceuticals for the time being.

The budget cuts affecting scientific activity in countries such as the United States and the fragility of centralised systems make decentralised and collaborative models a necessity. Science, intrinsically global, requires structures that can withstand local pressures. In this situation, Europe has the opportunity - and the duty - to lead a new paradigm where data is free, secure and accessible.

A study led by ISGlobal researchers has analysed how the loss of Arctic sea ice influences climate in isolation from other factors related to climate change. Their results, published in the journal Communications Earth and Environment, show that, on a time scale of decades, the loss of Arctic sea ice favours a drier climate in the southwestern United States -in particular in California-, especially in winter. This phenomenon would also affect the climate of Spain and Portugal, leading to wetter conditions in winter, although the effect is weaker.

A team from the University of Iowa (USA) has found a relationship between specific species of microbiota bacteria and the severity of multiple sclerosis. Specifically, a lower ratio between the quantities of Bifidobacterium and Akkermansia was related to the disease and to a worse course of the disease, both in mice and in two cohorts of patients and people without the disease. According to the authors, who publish the results in the journal PNAS, the finding could be used to improve the diagnosis and treatment of multiple sclerosis.