University of Barcelona

Craig Venter, the American biologist and entrepreneur who founded Celera Genomics to launch his own Human Genome Project in 1999 outside the public consortium, died Wednesday in San Diego at the age of 79, according to a statement from the J. Craig Venter Institute, which he led. Among other achievements, Venter completed the first full sequencing of a living organism’s genetic material and announced that he had succeeded in creating synthetic life.

The deliberate consumption of soil—known as geophagy—is a common practice among animals, either to supplement their diet or as a protective mechanism against intoxication and other digestive issues. For the first time, a research team with Spanish participation has documented this behaviour in Barbary macaques in Gibraltar, particularly during the summer, when tourist numbers peak. This has led the authors of the study, published in the journal Scientific Reports, to hypothesise that the purpose of geophagy is to mitigate the digestive discomfort caused by food provided by visitors.

The latest forecasts from the European Centre for Medium-Range Weather Forecasts (ECMWF) suggest that there is a likelihood that the phenomenon known as El Niño will return this year and that it will do so with greater intensity. In Europe, for June through August, the forecast indicates a slight tendency toward below-average precipitation in the northeast of the continent. As for the Iberian Peninsula, temperatures are expected to exceed the top quintile of the seasonal average. Although it is not yet certain that this will occur, forecasts for the coming months will either confirm or rule it out.

Permanent splits in chimpanzee groups are extremely rare—an event that occurs once every 500 years, according to genetic evidence. The journal Science reports on the split of the largest known group of wild chimpanzees following 30 years of observations. This involves the Ngogo chimpanzees in Kibale National Park (Uganda). The group shifted from cohesion to polarization in 2015 and eventually split into two distinct groups in 2018. From that point on, violence escalated, and members of one group killed at least seven males and 17 infants from the other. In the 1970s in Gombe (Tanzania), another case of this type was documented, but the chimpanzees had been fed by humans-

The so-called 'dark transcriptome' consists of non-coding RNA, i.e. RNA that does not provide instructions for building proteins. A study published in the journal Science Signaling used long non-coding RNAs (lncRNAs) and modified them to attenuate acute inflammation in mice and human cells. The authors are confident that this could open up a new field of therapeutic development.

A team in China has studied the ability of a test to detect the human papillomavirus (HPV)—responsible for the vast majority of cervical cancers—in menstrual blood from more than 3,000 women. The results indicate that the test is comparable to current screening performed in medical offices. According to the researchers, “Using menstrual blood for HPV testing is practical and non-invasive, allowing women to collect samples at home and thus potentially offering a practical way to expand access to screening.” The study is published in The BMJ. 

A study published in The BMJ suggests that the incidence of autism spectrum disorder (ASD) is comparable between boys and girls. The study included a sample of more than 2.7 million people born in Sweden between 1985 and 2020 who were followed from birth to a maximum age of 37. More than 78,000 were diagnosed with ASD. It was observed that boys are usually diagnosed between the ages of 10 and 14, five years earlier than girls. By the age of 20, the proportion of diagnoses is almost equal between the sexes. Before the age of 10, the ratio is 3:1 in favour of boys.

A phase 3 clinical trial conducted in China tested 210 patients with advanced non-small cell lung cancer—the most common type—to see whether the time of day when immunotherapy and chemotherapy were administered influenced their effectiveness. The data indicate that, on average, those who received therapy after 3 p.m. did not see their cancer worsen for 5.4 months. In contrast, those who received it before that time did not see their cancer worsen for an average of 11.7 months, almost twice as long. Overall, response rates were 56.2% and 69.5%, respectively. The results, published in Nature Medicine, suggest that scheduling therapy early in the day may offer a simple and cost-free way to improve treatment efficacy.

The American Psychiatric Association has unveiled the new features of the forthcoming Diagnostic and Statistical Manual of Mental Disorders (DSM) in five articles published in The American Journal of Psychiatry. Among the highlights are the proposed change of name — it will become the Diagnostic and Scientific Manual — and the intention for it to be more dynamic, incorporating biomarkers for diagnosis and integrating the socioeconomic, cultural and environmental determinants of health. According to the authors, the aim is to enable a more personalised and inclusive clinical practice, aligned with scientific rigour. The most recent update was published in 2022 with the DSM-5-TR, and specialists are currently unaware of the date of the next edition, as they reported during a briefing with journalists.

Before being published, studies written by female researchers are spend a longer time in peer review than articles by male authors, according to an analysis of more than 36 million publications in biomedical and life science journals. The median peer review time is between 7.4% and 14.6% longer for female authors than for male authors in most disciplines, says the analysis published in PLoS Biology.