Spanish National Research Council (CSIC)

A team of researchers has used embryonic stem cell engineering to create a bipaternal mouse - a mouse with two male parents - that lived to adulthood. Their results, published in the journal Cell Stem Cell, show how targeting a particular set of genes involved in reproduction enabled this breakthrough in unisexual reproduction in mammals.

A team of researchers from the USA has analyzed the B lymphocytes of seven healthy people in whom no exposure to H5 influenza viruses, such as the avian flu virus, had been documented. The results show that they present antibodies capable of recognizing this type of virus, which, according to the authors, could represent “a first line of defense” in the event of a pandemic. The results are published in the journal Science Immunology.

A study in mice reveals that immune cells in the brain 'engulf' microplastics, forming clumps that can cause brain clots. The findings, published in the journal Science Advances, highlight how microplastics can indirectly damage the brain by disrupting blood flow, rather than directly infiltrating brain tissue cells. 

An assessment of the extinction risk of freshwater fauna, covering more than 23,000 species, reveals that around 24% of the species studied are at risk of extinction. The analysis, published in Nature, identifies the main threats from pollution, dams, agriculture and invasive species. Decapods - such as freshwater crabs and shrimps - have the highest percentage of threatened species (30 %), followed by freshwater fish (26 %) and odonates - such as dragonflies (16 %).

Meeting in the city of Windoek (Namibia), the plenary of the IPBES - Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services - has ratified two new reports: the Nexus Assessment and the Transformative Change Assessment. Three of their authors explained the main findings and the changes they propose at a briefing organised by SMC Spain.

Thirty eight scientists from different specialties, including Craig Venter, a pioneer in the creation of artificial synthetic life, have written an article in the journal Science in which they assess the possibilities of synthesizing mirror organisms, but also warn of the risks they pose. This type of microorganisms, which would present a mirror structure to that currently found in nature, would have potential applications due to their resistance to biological degradation. However, they would also pose a danger because they would not be recognized by our defenses and could spread in ecosystems. Scientists call for more research and a broad debate, and warn that until more is known, this type of organism should not be created. 

A team of researchers has analyzed more than 300 human genomes from the last 50,000 years and has concluded that most of the gene flow we received from Neanderthals is attributable to a single period, which probably occurred between 50,500 and 43,500 years ago. In addition, Neanderthal inheritance underwent rapid natural selection in subsequent generations, especially on the X chromosome, according to a study published in Science.

Researchers in China have analysed data from more than 4,500 people and identified 13 proteins linked to brain ageing. In addition, changes in protein concentrations in the blood tend to peak at ages 57, 70 and 78. According to the authors, who publish the results in the journal Nature Aging, these ages may reflect transitions in human brain health at specific ages, and could therefore be important for designing possible interventions in the brain ageing process.

More than three-quarters of the earth's land surface experienced drier climates between 1990 and 2020 compared to the previous three decades, according to a new report by the United Nations Convention to Combat Desertification. Over the past 30 years, 40.6 percent of the global landmass, excluding Antarctica, is classified as drylands, three percentage points more than the previous three decades. The report, which is being presented at the COP16 on desertification being held in Riyadh, Saudi Arabia, also shows that 2.3 billion people were living in drylands in 2020, a population that could rise to 5 billion by 2100 under a worst-case climate change scenario.

According to a study published in Nature Medicine, deep brain stimulation of the lateral hypothalamus improves walking and promotes recovery in humans and rodents with spinal cord injuries. In humans, the authors tested this technique on two patients who relied on assistive devices and had difficulty walking; both showed improved performance in the ten-meter and six-minute walking tests. Combined with rehabilitation, the patients experienced recovery that persisted even after the deep brain stimulation was turned off.