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An international team involving ISGlobal has analyzed climate data from 50 editions of the Tour de France between 1974 and 2023. The results show that, during the month of July, the risk of heat stress has increased over the years, with the last decade seeing the highest number of extreme heat episodes. In the locations analyzed, the Tour has so far managed to avoid conditions of maximum risk to health, but according to the researchers, it has been "an extremely fortunate race. With record heat waves becoming more frequent, it seems only a matter of time before the Tour faces days of extreme heat stress that will test current safety protocols. The study, published in Scientific Reports, used the Tour de France as an example of the challenge that rising temperatures associated with climate change pose for the organization of sporting events in the summer.

A study published in PNAS reveals the effects of large-scale wildfire smoke and aerosols from major volcanic eruptions on global atmospheric temperatures. Using satellite observations, the team estimated the temperature disturbances associated with the 1991 eruption of Mount Pinatubo in the Philippines, the 2019–2020 Australian wildfires, and the 2022 eruption of the submarine Hunga Tonga volcano in Tonga. All three events had measurable impacts on global atmospheric temperatures. Sulfate particles from Pinatubo caused cooling in the troposphere and warming in the stratosphere, confirming previous measurements. Aerosols from the Australian wildfires —though only about 5 % of the aerosol mass emitted by Pinatubo— also produced both effects, while water vapor from Hunga Tonga led to tropospheric cooling.

Counties in the United States closest to operating nuclear power plants have higher cancer mortality rates than those further away, according to a new study led by the Harvard T.H. Chan School of Public Health, published in Nature Communications. Using data from 2000 to 2018, they assessed spatial patterns of cancer mortality in relation to proximity to nuclear facilities, taking into account socioeconomic, environmental, and health factors. Cancer mortality was higher in both men and women, with the strongest associations among men aged 65 to 74 and women aged 55 to 64. The findings do not imply causality.

Although cancer is a common cause of death in domestic cats, little is known about the range of genes affected and how they compare with the oncogenome in humans. A study published in Science sequenced cancer-related genes in 493 samples from 13 different types of feline cancer to obtain a clearer picture of the feline oncogenome. The genes were also compared with known cancer-associated mutations in humans.

The study of psychedelic drugs in pharmacological treatments had its eureka moment with chemist Albert Hofmann's famous bike ride under the influence of LSD in 1938 and then developed over decades, but with Richard Nixon it was shelved. In recent years, it has resurfaced in hospitals and laboratories around the world. Last week, the Congress of Deputies hosted a conference on these substances. We explain what they are, what they are used for, the current state of research, and their risks, with the help of expert sources.

In February 2025, lithium concentrations suddenly increased around 96 km above sea level some 20 hours after a SpaceX Falcon 9 launch vehicle re-entered the atmosphere. This is the first direct detection of pollution in the upper atmosphere due to the re-entry of a spacecraft, according to a study published in Communications Earth & Environment. Lithium is used in spacecraft components, but it is only found naturally at these altitudes in trace amounts, and its accumulation could have consequences on the climate.

A new cardiac valve stent can expand on its own, according to preclinical tests conducted in piglets; the pediatric device doubled in size as the animals matured. As the authors note in their study published in Science Advances, this offers the possibility of adapting to the rapid growth of the hearts of babies and young children with congenital conditions. The stent, which is based on a spring-like expansion mechanism, could eliminate the need for repeated surgeries in pediatric patients.

On social network X (formerly Twitter), when users select the ‘for you’ option, the algorithm tends to steer them towards more conservative political options, according to research conducted with nearly 5,000 participants in the United States in 2023. The authors randomly assigned users to either an algorithmic or chronological feed for seven weeks. The switch from chronological to algorithmic feed increased engagement and shifted political opinion towards more conservative positions, especially on political priorities, perceptions of criminal investigations into Donald Trump, and opinions on the war in Ukraine. Conversely, switching from the algorithmic feed to the chronological feed had no comparable effects. ‘Initial exposure to X's algorithm has persistent effects on users' current political attitudes,’ say the authors of the study, published in Nature.

Human-induced climate change amplified the intensity and extent of the rainfall that affected Valencia during the October 2024 dana, according to a new attribution study involving several Spanish research centres. Using climate simulations, the study, published in Nature Communications, shows that present-day global warming conditions increased precipitation intensity by 21 %, expanded the area receiving more than 180 millimetres of rain by 56 %, and raised the total rainfall volume in the Júcar River basin by 19 % compared to a pre-industrial scenario. The authors highlight “the urgent need for effective adaptation strategies and improved urban planning to reduce the growing risks associated with extreme hydrometeorological events in a rapidly warming world.”

Dimethyltryptamine (DMT) is responsible for the psychedelic effects of ayahuasca. According to the results of a phase IIa clinical trial published in Nature Medicine, this molecule improved depressive symptoms in adults with depression after one dose. The trial included 34 people, 17 of whom received intravenous DMT. This second group showed greater improvements in depressive symptoms than the control group. After two weeks, in the second part of the trial, DMT was administered to all participants and the antidepressant effects lasted for three months. Adverse effects were mainly pain at the injection site, nausea and transient anxiety.