People with type 1 and type 2 diabetes are at greater risk of sudden cardiac death

A study published in the European Heart Journal shows that people with type 1 and type 2 diabetes have a higher risk of sudden cardiac death than those without these diseases. In addition, their life expectancy is lower. The research analysed data from 6,862 cases of sudden cardiac death in Denmark in 2010, and concluded that the incidence of these deaths is 3.7 times higher in people with type 1 diabetes than in the general population, and 6.5 times higher in people with type 2 diabetes. Those under the age of 50 were at the highest risk.

04/12/2025 - 01:05 CET
Expert reactions

251204 diabetes albert EN

Albert Goday Arno

Professor of Endocrinology in the Department of Medicine and Life Sciences at Pompeu Fabra University, Emeritus Head of the Endocrinology and Nutrition Service at Hospital del Mar in Barcelona and President of the Advisory Council on Diabetes in Catalonia of the Generalitat de Catalunya

Science Media Centre Spain

This study is based on solid data and methods. It analyses Denmark's national registry, which includes all individuals with both type 1 and type 2 diabetes.

It is consistent with previous studies that emphasise the increased risk that diabetes still poses today in terms of cardiovascular problems. What is new about this study is that it specifically examines a very specific problem: sudden death.

From a methodological point of view, there are no significant limitations to consider. It is important to note that the data refer to 2010 and, fortunately, the quality of care available to people living with diabetes has improved significantly over the last 15 years, from 2010 to 2025.

The relevance of this study in practice/clinical settings highlights the need to improve cardiovascular preventive measures. The recommendations we can make based on this are to improve the care offered to people living with diabetes.

The author has declared they have no conflicts of interest
EN

251204 diabetes gemma EN

Gemma Rojo Martínez

Senior researcher and group leader at CIBER for Diabetes and Associated Metabolic Diseases (CIBERDEM), researcher at the Regional University Hospital of Malaga and at IBIMA-Bionand platform

Science Media Centre Spain

In general, the population-based approach of this study makes it extremely robust: there is no sampling; the entire population of a whole country is used to extract results.

The main limitations are inherent in the design; causality cannot be proven, and results based on medical records always have the inaccuracy of the cause of death, even of the accurate diagnosis of the diseases investigated. Perhaps most importantly, the data are from about 15 years ago, when certain cardioprotective drugs for diabetes (sodium-glucose cotransporter 2 inhibitors, or SGLT2 inhibitors) were not yet in use, although they are widely used today.

In any case, the study highlights the need for surveillance and prevention of SCD [sudden cardiac death] in young patients with diabetes.

The author has declared they have no conflicts of interest
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European Heart Journal
Publication date
Authors

Tobias Skjelbred et al.

Study types:
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  • Peer reviewed
  • Observational study
  • People
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