Clínic Hospital
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Head of the Cardiology Department at the Hospital Clínic de Barcelona and researcher at the National Centre for Cardiovascular Research (CNIC) and at the August Pi Sunyer Biomedical Research Institute (IDIBAPS)
Senior Consultant at the Department of Preventive Medicine and Epidemiology at Hospital Clínic in Barcelona, Professor of Public Health and Dean of the Faculty of Medicine and Health Sciences at the University of Barcelona
Neurologist at the Hospital Clínic in Barcelona
Head of Microbiology at Hospital Clínic in Barcelona, associate professor at the University of Barcelona, and researcher at ISGlobal Barcelona
Psychiatrist and researcher at the Bipolar and Depressive Disorders Unit of the Hospital Clínic de Barcelona
Head of the Arrhythmias and Physical Activity research group at IDIBAPS, cardiac electrophysiologist at Hospital Clínic Barcelona, associate professor of Medicine at the University of Barcelona and researcher at CIBERCV.
Director of the Institute of Neurosciences at Hospital Clínic, Professor of Psychiatry at the University of Barcelona and researcher at IDIBAPS and CIBERSAM
Neurologist at the Neuroimmunology Unit of the Neurology Department at Hospital Clínic de Barcelona
Psychiatrist and researcher at the Depressive and Bipolar Disorders Unit of the Hospital Clínic de Barcelona
Assistant Doctor of Psychiatry and postdoctoral researcher at the Bipolar and Depressive Disorders Unit of the Psychiatry and Psychology Department of the Hospital Clínic de Barcelona.
Professor of Medicine at the University of Barcelona and coordinator of the Central Sensitisation Unit at the Hospital Clínic de Barcelona.
Research Professor at IDIBAPS-Hospital Clínic de Barcelona and Scientific Director of CIBEREHD - Carlos III Health Institute
Clinical psychologist in the Department of Child and Adolescent Psychiatry and Psychology at Clínic Hospitaland researcher at IDIBAPS, University of Barcelona
Bioinformatics Specialist at Hospital Clínic de Barcelona
Head of the HIV-AIDS unit, Hospital Clínic-Barcelona
Endocrinologist at the Obesity Unit of the Endocrinology and Nutrition Service of the Hospital Clínic de Barcelona and former member of the Spanish Obesity Society (SEEDO).
Head of the Immunology Service
Physician at the Gynecological Oncology Unit at the Hospital Clínic of Barcelona, scientific coordinator at the Clinical Institute of Gynecology, Obstetrics and Neonatology (ICGON) and associate professor at the University of Barcelona
Clinical psychologist at the Psychiatry and Psychology Service of the Hospital Clínic de Barcelona and member of the research group Imaging of mood and anxiety disorders at IDIBAPS
Specialist in Immunology at the Immunology Department of the Hospital Clínic de Barcelona, specialising in immune response to anti-infectious vaccines
IDIBAPS researcher and scientific director of the HIV Unit at Hospital Clínic de Barcelona
Head of the Neurology Department at Hospital Clínic de Barcelona and secretary of the Spanish Society of Neurology's Study Group on Behaviour and Dementia
Rheumatologist and Head of the Autoimmune Diseases Service at Hospital Clínic de Barcelona
Head of the Neurology Department at the Hospital Clínic of Barcelona
The administration of intismeran, a personalised therapeutic cancer vaccine developed from each patient’s tumour, together with pembrolizumab immunotherapy following surgery for high-risk melanoma, reduced the risk of recurrence or death by 42 per cent. This phase 3 clinical trial, funded by Moderna and Merck Sharp & Dohme, involved 1,137 patients at very high risk of recurrence who had undergone surgical removal of their melanoma. The companies released preliminary data in August in a press release, and the full results are due to be presented this Saturday at the European Society for Medical Oncology (ESMO) Congress being held in Madrid. Ahead of the announcement, the data were leaked yesterday and the share prices of both companies fell. The scientific paper is due to be published in The New England Journal of Medicine.
Using clinical and genetic data from more than 10,000 Australians with depression, an international team has found that nearly 25 per cent suffered from what they have termed ‘circadian depression’ – a subtype previously proposed by the scientific community that is characterised by disrupted sleep-wake cycles, reduced daytime activity and low energy levels. In the study, those identified as having this form of depression reported an earlier age of onset, more severe clinical features and weight gain during depressive episodes. The authors, whose study is published in The British Journal of Psychiatry, state that these findings “support the apparent validity and potential clinical utility of a circadian subtype of depression as a clinical profile”.
Among the migrants who have been in Ceuta for several weeks, there are confirmed or suspected cases of tuberculosis, chickenpox, scabies and gastroenteritis. Specialists in public health, epidemiology and infectious diseases explain to SMC España the basic recommendations that must be followed when providing care for this population.
A study published in JAMA Network Open has examined whether the colorectal cancer screening programme based on faecal immunochemical testing, launched in the Basque Country, was associated with lower mortality from this cause over a 21-year period. The study — a retrospective, population-based cohort study — included all residents of the Basque Country (2.2 million people) between 2004 and 2024. The screening programme, aimed at people aged between 50 and 69, was launched in 2009. According to the study, screening was associated with a 50 per cent reduction in mortality from this cause among adults in that age group. Furthermore, a significant change in the trend was observed just three years after the programme began.
The range of CRISPR tools for genome editing can extend beyond nature-inspired designs thanks to proteins designed using artificial intelligence. A new study by Nobel laureate Jennifer Doudna’s team, published in Science, describes the design of synthetic RNA-guided nucleases, with sequences substantially different from those found in nature, which match or exceed the activity of their natural counterparts whilst offering novel properties.
Pancreatic ductal adenocarcinoma (PDAC), the most common form of pancreatic cancer, is an aggressive tumor that is often diagnosed at advanced stages. Some people are at high risk of developing it due to a hereditary predisposition (10% of cases) or an injury. A new Phase 1 clinical trial has tested, in high-risk patients, a vaccine targeting several mutations in the KRAS gene responsible for more than 90% of these tumors. The vaccine has been shown to be safe and has stimulated specific immune responses, detectable in the blood up to two years later, in 90% of the study participants. The study is published in Cancer Discovery.
An international team has published the five-year follow-up results of a phase 2b clinical trial testing a personalised cancer vaccine in combination with standard immunotherapy treatment for melanoma. After this period, the probability of cancer recurrence was around 50% lower in the group of patients who received the vaccine. Furthermore, the probability of metastasis was almost 60% lower. The results are being presented at the ASCO (American Society of Clinical Oncology) conference and published in the Journal of Clinical Oncology.
In 2023, 1.17 billion people suffered from a mental health disorder, compared to 599 million people in 1990, according to a global study published in The Lancet. Women experienced higher rates of anxiety and depression, while neurodevelopmental and behavioral disorders—such as ADHD or autism—are more common in men. The highest incidence was observed among those aged 15 to 19, which, according to the authors, underscores the need for early prevention and targeted support for this age group.
The latest reports from the European Centre for Disease Prevention and Control (ECDC) indicate a rise in bacterial sexually transmitted infections (STIs) across Europe. In 2024, notifications of gonorrhoea and syphilis, along with congenital syphilis, reached their highest levels in more than a decade, reflecting sustained transmission across multiple countries. Gonorrhoea has increased by more than 300 % over the past 10 years, with Spain among the countries with the highest rates, while syphilis has risen by around 100 %, with Spain also ranking second highest. Men who have sex with men are the most affected population group for both infections. Congenital syphilis increased by almost 250 %, described as “one of the most concerning findings” by two ECDC experts during the briefing presenting the results. Possible contributing factors include reduced condom use, an increase in sexual partners, as well as higher levels of testing.
The eyes are connected to the brain via the retina, which makes it a potential pathway for brain stimulation. A study published in Cell Reports Physical Science has used contact lenses equipped with a system for transcorneal electrical stimulation to treat depression in animal models of the disorder. Mice fitted with the device showed behavioural improvements, including increased sociability, as well as physiological changes, such as the restoration of altered neural connections. The results were comparable to those obtained with fluoxetine —known commercially as Prozac— administered for three weeks in one of the mouse groups.