Reacción a "Nobel Prize in Medicine or Physiology awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi for understanding how the immune system is kept under control without attacking organs"

The awarding of the Nobel Prize for studies on regulatory T cells (Tregs) and peripheral tolerance is a long-awaited recognition in the field of immunology.

These cells play a fundamental role in maintaining immune tolerance and ensuring that the immune system respects the body's own tissues, preventing it from attacking them and contributing to the balance between defence and self-regulation.

Their study has been decisive in better understanding not only autoimmune diseases, but also the mechanisms of immune evasion in cancer and the processes that allow transplant acceptance. Thanks to these discoveries, new opportunities have opened up in recent years to develop more specific and safer immunomodulatory therapies, with a direct impact on improving human health.