Reacción a "Mutations caused by pollution in lung cancer in non-smokers revealed"

This study highlights the importance of controlling air pollution to prevent respiratory diseases. In this case, it shows that air pollution can cause damage to people's genetic material, which could increase the risk of lung cancer in people who have never smoked. Despite this, smoking remains the most important risk factor for developing lung cancer. We must therefore continue to work towards achieving environments free of tobacco and other air pollutants.

The article is of very high quality. It combines molecular information on lung cancer in non-smokers with information on the degree of air pollution in 28 different geographical areas around the world.

It has previously been reported that non-smokers in Asia show an increase in EGFR gene mutations in areas with high air pollution. This study highlights the importance of air pollution as a causative agent of cancer, reinforcing the need to control air pollution to prevent respiratory health problems, in this case due to its role in lung cancer in non-smokers.

[Regarding possible limitations] This study focuses mainly on the role of air pollution in lung cancer in the non-smoking population, but the effect of air pollution on the smoking population may also be relevant, as it could cause synergism, something that has not been explored in this study, and tobacco remains the main (and preventable) risk factor for developing lung cancer today.