Autor/es reacciones

Toni Gabaldón

ICREA research professor and head of the Comparative Genomics group at the Institute for Research in Biomedicine (IRB Barcelona) and the Barcelona Supercomputing Center (BSC-CNS).

I find it an interesting study that suggests that fecal transplantation could help reduce the presence of antibiotic-resistant bacteria. This is an important application, given the high risk of post-transplant infections and the difficulty of treating multi-resistant bacteria. 

The study, however, is very preliminary, with only a dozen patients. The groups compared receive fecal transplantation treatment at different times and are not compared with alternative pretreatments. It is important to remember that the aim of a phase 1 clinical trial is primarily to demonstrate safety and establish doses, not so much to demonstrate the efficacy of a treatment. Although the data point to high efficacy, we must wait for more advanced phases.

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