Daniel J. van Wamelen
Clinical Senior Lecturer in Neuroscience and Honorary Consultant Neurologist, Institute of Psychiatry, Psychology & Neuroscience, King’s College London (UK)
The findings in this study are interesting and appear to be based on solid research with conclusions well supported by the data. However, it is important to highlight that the symptoms examined in this study are possible early signs of Parkinson’s disease, not definitive indicators that someone will go on to develop it. The study did not track whether participants were diagnosed with Parkinson’s later on.
Many of the individual symptoms noted, such as sleep disturbances, constipation, and mood changes, are common in the general population. While the study found that people who ate more ultra-processed foods tended to report more of these non-motor symptoms, it did not find a direct increase in the risk of Parkinson’s disease itself. That said, having more of these symptoms suggests a higher risk over time. For example, a person experiencing a combination of REM sleep behaviour disorder, constipation, and depressive symptoms has a higher likelihood of developing Parkinson’s down the line, but the risk is not absolute. To better understand the long-term implications, we would need a longer follow-up to see how many participants go on to develop Parkinson’s and how this is associated with their diet.
In short, this is an interesting piece of research addressing important questions. But the connection to Parkinson’s disease should be viewed with caution until more definitive evidence becomes available.