Spanish researchers publish the “human repairome,” a catalog of the traces left by DNA repair after breaks
The very functioning of the cell itself or stresses such as those caused by sun exposure can cause breaks in our DNA, which must be repaired. A study developed by the CNIO has completed a catalog of how each of our genes affects the repair of some of these breaks and how they influence the resulting "scars." The catalog, which they have called the "human repairome," will be openly available. According to the researchers, whose work is published in Science, it will have "implications for human health, including the biology and treatment of cancer, as well as for efforts toward total control of CRISPR-Cas gene-editing technologies".
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