Reacción a "Nobel Prize in Medicine or Physiology awarded to Ambros and Ruvkun for the discovery of microRNAs and their role in gene regulation"

It is a great success and a joy that this year's Nobel Prize in Medicine has been awarded to Victor Ambros and Gary Ruvkun for their discovery of microRNAs and their role in post-transcriptional gene regulation. This finding is of great importance, transforming our understanding of the regulation of gene expression and attributing critical functions to a fraction of the human genome that was previously considered 'junk DNA' because it does not code for proteins. These small non-coding RNAs play fundamental roles in virtually all cellular processes, including development, immunity and disease progression, by simultaneously regulating multiple genes, generating potent functional effects. The impact of microRNAs in medicine is evident, positioning them as key molecules in the development of new therapies for complex diseases, such as cancer and autoimmune diseases, among many others.