pesticides

A team from the Vall d'Hebron Institute of Oncology in Barcelona has published a study examining the impact of the exposome—changes in lifestyle and environmental factors—on early-onset colorectal cancer through epigenetic signatures. By analyzing methylation patterns in patients, they confirmed previously identified risk factors such as diet, educational level, and tobacco use. Additionally, they identified a significant association with picloram, a widely used herbicide. The results are published in Nature Medicine.

A study published in Science shows a global increase in the toxicity and ecological harm caused by pesticides, contrary to the United Nations’ goal of halving pesticide-related risks by 2030. The authors analysed Total Applied Toxicity (TAT), which accounts for both pesticide use and toxicity, at a global scale between 2013 and 2019. The data covered the risks of 625 pesticides across eight species groups and 65 countries, representing 79.4% of global cropland. TAT increased in six of the eight species groups, including all invertebrate groups and terrestrial plants, and only Chile would meet the target of reducing pesticide risk by 50% by 2030.

The European Commission will renew the authorisation of the pesticide glyphosate in the European Union for 10 years, subject to "new restrictions and conditions". Following EU procedure, the announcement was made after member states failed to reach the majority required to renew or refuse approval.

The decline of insects in Central and Western Europe in recent years is mainly due to human activities and the intensification of agriculture, according to a study funded by three companies (Bayer, BASF and Syngenta) that manufacture pesticides. The paper, published in PLoS ONE, summarises an analysis of 82 other published studies and explains the causes of population declines in two groups of insects: carabids (ground beetles) and lepidopterans (including moths and butterflies). The authors estimate that "anthropogenic activities in general" are most responsible for this decline, followed by agricultural intensification (including pesticides) and climate change in third place.

A study in Spanish children, with follow-up from pregnancy to adolescence, has found an association between children's exposure to pesticides and fungicides and earlier breast development in girls and genital development in boys. The work has been carried out by the University of Granada (UGR), the Institute for Biosanitary Research (ibs.GRANADA) and CIBERESP (ISCIII).