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Drugs to treat erectile dysfunction may be associated with a reduced risk of Alzheimer's disease, according to an observational study of nearly 270,000 men, published in Neurology. The research does not prove that these drugs reduce the risk of Alzheimer's, but only shows an association.
Two teams of researchers have separately described a population of memory lymphocytes that may be responsible for the persistence of allergies over time. The work has analysed responses to allergens such as those present in peanuts, dust and birch. According to the authors, whose research is published in Science Translational Medicine, these cells could serve as a target for the treatment of various types of allergies.
A study in South Korea followed more than 160,000 women for more than eight years and concluded that infection with different strains of human papillomavirus is associated with a fourfold increase in the relative risk of dying from cardiovascular causes. According to the authors, "it could be that the virus causes inflammation in the blood vessels, contributing to blockage and damage to the arteries". The findings are published in the European Heart Journal.
The European Centre for Disease Prevention and Control (ECDC) reported that on January 29th, Spanish authorities notified a possible case of human infection with swine flu virus A(H1N1)v in a worker from a Catalan pig farm. After being diagnosed with bronchitis, subsequent laboratory analyses confirmed it as swine flu A(H1N1)v. The ECDC informs that the patient has fully recovered, and to date, no new cases have been detected among close contacts or among the worker's colleagues at the farm.
In 2010, nearly 1,000 sub-basins around the world were facing water shortages. But when considering not only water quantity, but also water quality, this figure rises to more than 2,500, according to a study published in Nature Communications. By 2050, the authors estimate that up to a third of sub-basins will face severe shortages of clean water, which could affect 3 billion people. Southern China, Europe, North America and Africa will be the most affected regions.
Global average surface temperatures may have already surpassed the 1.5°C warming mark and could exceed 2°C by the end of the decade, as suggested by an article published in Nature Climate Change. The projections are based on 300 years of preserved ocean temperature records found in Caribbean sponge skeletons.
In a clinical trial of nearly 5,000 children aged 5-36 months, a new malaria vaccine - called R21/MatrixM - reduced symptomatic cases by 68-75% over the following year. According to the authors, the vaccine will be inexpensive and could contribute to a substantial reduction in malaria suffering and deaths in sub-Saharan Africa. The results of the phase 3 trial are published in The Lancet.
By 2050, there will be more than 35 million new cases of cancer worldwide, an increase of 77% from the 20 million cases reported in 2022. These are projections made by the WHO's International Agency for Research on Cancer (IARC), which has published the latest estimates of the global burden of cancer. Using data from 185 countries, IARC estimates that in 2022 lung cancer was the most common cancer worldwide, with female breast cancer in second place, followed by colorectal, prostate and stomach cancer. The authors stress the urgent need to address inequalities around these diseases.
In an anonymous online survey of dog owners in Denmark, 38% of respondents said they administered cannabinoid products - such as cannabidiol drops - to their pets without a prescription, even though their use is not legal in animals. Reasons given included pain, behavioural problems and allergies in their dogs. Some 2,000 people responded to the survey, the results of which are published in the journal PLoS ONE.
Researchers have described five cases of people in the UK who developed Alzheimer's-like dementia after being treated as children with growth hormone from cadavers. The treatment was administered between 60 and 40 years ago. This suggests that the disease could be transmitted. However, the authors point out that this is a very rare occurrence and could have been caused by repeated exposure to a type of hormone that is no longer used. The results are published in the journal Nature Medicine.