José Antonio Márquez
Director of the Crystallography Platform at the European Molecular Biology Laboratory (EMBL) in Grenoble.
This work provides an answer to one of the great challenges in biology, how to predict the structure of proteins from the sequence encoded in DNA with a high degree of reliability. Structure predictions for hundreds of millions of different proteins are now available worldwide in the EMBL EBI databanks and the prediction programmes and algorithms developed by these teams have become an indispensable tool in most biology laboratories. They allow us, for example, to understand the relationship between the structure and function of a protein, why certain genetic mutations can lead to disease, or how proteins interact with each other to carry out more complex functions. It was an expected award and demonstrates how new artificial intelligence technologies can contribute to solving very complex scientific problems.