Autor/es reacciones

Jordi Cano Ochando

Senior Scientist, Immunology Laboratory, Carlos III Health Institute

Regulatory T cells (Tregs) suppress the immune response and are necessary to prevent autoimmune diseases and organ transplant rejection. The existence of these cells was first described by Richard Gershon at Yale University in 1972. However, he was unable to identify them, and after his death in 1983, suppressor T cells were forgotten until 1995, when Shimon Sakaguchi described the interleukin-2 receptor (CD25) as the “identity card” of regulatory T cells. Thirty years have passed since Sakaguchi's discovery, and regulatory T cells are now used as cell therapy to treat various immune-based diseases.

 

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