Joaquim Raduà
Psychiatrist and head of the Imaging of Mood and Anxiety Disorders research group at IDIBAPS
This study has several strengths, including the combination of data from different national registers in Sweden, and the within-individual design (i.e. studying whether the risk of violent crime in individuals was different when they took beta-blockers than when they did not).
I would like to stress that this is an observational study, so we do not know whether the decreased risk of violent crime is due to beta-blockers or to other factors that the authors could not take into account. For more evidence on whether beta-blockers actually decrease the risk of violent crime, more randomised trials should be done.
Although previous studies are rather sparse, they also point to a possible benefit of beta-blockers in reducing aggression, at least in the short term.
To better understand whether beta-blockers could be beneficial in reducing aggression, we should first have more randomised trials studying both short- and long-term efficacy and side effects.