Autor/es reacciones

Alberto Ascherio

Professor of Epidemiology and Nutrition at the TH Chan School of Public Health, Harvard University and Professor of Medicine at Harvard Medical School 

This is a high-quality study that stands out mainly for its sample size. The results confirm previous findings that people with a history of cold sores have a higher risk of developing Alzheimer's disease and that this risk appears to be reduced in people who receive antiviral treatment. This is an observational study based on electronic data of varying quality, so the conclusions cannot be considered definitive. For example, the vast majority of cold sore episodes are not reported in medical records, so the study's conclusions apply to a highly selected subgroup of individuals with clinical episodes of cold sores, perhaps due to clinical severity or the presence of other factors. For this reason, it would be premature for people with cold sores to worry about having an increased risk of Alzheimer's disease. However, there is growing evidence that viral infections may affect the risk of Alzheimer's disease, and it is important to initiate more definitive research.

EN