Jesús Montero-Marín
Researcher Miguel Servet at the Parc Sanitari Sant Joan de Déu and visiting researcher at the Department of Psychiatry at the University of Oxford (United Kingdom)
The study published in The Lancet Psychiatry represents a major advance in the treatment of resistant depression. Mindfulness-based cognitive therapy (MBCT) showed higher effectiveness compared to treatment as usual, even in patients who had not remitted after previous intensive interventions. The study methodology is robust, with a randomised, controlled design and 34-week follow-up, which supports the robustness of its conclusions.
This work provides conclusive evidence that MBCT can be an effective and cost-effective second-line treatment option in structured clinical settings. Although direct extrapolation to other health systems, such as the Spanish one, should be done with caution and requires further research, the model is scalable and compatible with primary mental health care. Its implementation could lead to a substantial improvement in the continuity of care for cases of difficult-to-treat depression.